4 students died and at least eight others were injured when a student dormitories room exploded and then collapsed during an early morning fire at an Ohio college.

The university said that a total of six students were killed, including a 16-year-old male student who had attended the Ohio school, and another four students who were taken to the hospital.

A fifth student who was in the room with the other two died at the hospital, the university said.

The Ohio National Guard responded to the scene at the Ohio State University, which is located near the University of Central Ohio.

The National Guard reported that it was responding to the fire at the university after receiving information from the State Fire Marshal.

The University of Dayton confirmed the student dorm was the Ohio University campus.

The school said in a statement that the student was found in the building with multiple injuries and was pronounced dead.

Authorities did not say if the other students were injured.

The building was completely destroyed.

The fire, which started shortly after 1:30 a.m., destroyed the building, according to the school.

The students were in their dormitory rooms when the fire broke out, officials said.

They were able to escape the blaze, but were later found to be in serious condition, officials told the Columbus Dispatch.

The other dormitory was not damaged.

Officials said it was not immediately clear if any of the injured students were students.

The cause of the fire was under investigation.